Semax(SEMAX)
Nootropic research peptide studied for cognitive performance pathways in laboratory research.
Mechanism of action
Semax is a synthetic heptapeptide fragment of ACTH (4–10). Published research describes its activity on BDNF expression and central monoaminergic systems in animal and in-vitro models, with literature exploring cognitive-performance and neuroprotection endpoints.
Semax is a tiny 7-amino-acid piece of a natural stress hormone (ACTH). In animal studies it bumps up BDNF — a protein that helps brain cells grow and form new connections — which is why researchers study it for memory and learning models.
Research areas
- · Memory, focus, and learning in animal models
- · How the brain grows and maintains new connections
- · How brain cells survive stress or injury
History & discovery
Developed at the Institute of Molecular Genetics in Moscow in the 1980s. It has been studied in Russian clinical research since the 1990s but remains a research compound outside that context.
Reconstitution & handling
Lyophilized peptides are typically reconstituted with bacteriostatic water and stored refrigerated after reconstitution. Use the dosing calculator to work out concentrations for your research preparation.
Open reconstitution calculatorAssay & QC notes
Each lot is tested by reversed-phase HPLC for purity, confirmed by mass spectrometry for identity, and screened for endotoxin contamination.